CELL BANKS PREPARATION IN BIOPHARMACEUTICALS PRODUCTION
نویسندگان
چکیده
منابع مشابه
Plant-based production of biopharmaceuticals.
Plants are now gaining widespread acceptance as a general platform for the large-scale production of recombinant proteins. The first plant-derived recombinant pharmaceutical proteins are reaching the final stages of clinical evaluation, and many more are in the development pipeline. Over the past two years, there have been some notable technological advances in this flourishing area of applied ...
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The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant growth in the production and approval of recombinant proteins such as interferons (IFN α, β, and γ) and growth hormones. The production of biopharmaceuticals, known as bioprocess,...
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The use of plants and other botanicals as a source of medicines exists of the earliest stages of civilization. Despite great advances in synthetic organic chemistry, it is estimated that about onefourth of present day prescription drugs still have a botanical origin. Recently, and through modern biotechnology, there has been a revival of interest in obtaining new pharmaceuticals from botanical ...
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Biopharmaceuticals are often produced by recombinant E. coli or mammalian cell lines. This is usually achieved by the introduction of a gene or cDNA coding for the protein of interest into a well-characterized strain of producer cells. Naturally, each recombinant production system has its own unique advantages and disadvantages. This paper examines the current practices, developments, and futur...
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ژورنال
عنوان ژورنال: Postępy Mikrobiologii - Advancements of Microbiology
سال: 2019
ISSN: 0079-4252,2545-3149
DOI: 10.21307/pm-2019.58.1.087